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Stimvia URIS I Nerve Stimulator
The URIS I nerve stimulator is intended for the treatment of lower urinary tract symptoms (urgency, frequency, nocturia, incontinence) using non-invasive electrical transcutaneous neuromodulation of the peripheral nerves or through percutaneous electrical stimulation of the tibial nerve.
BROCHURE
PRODUCT SUPPORT
22-26%
Urination Frequency: Patinets experienced a reduction in the number of urination episodes per day by approximately 22-26% after 12 weeks of treatment
87%
Urgency (Sudden urge to urinate): 87% of patients experience significant improvement, with a reduction in the number of episodes of intense, urgent need to urinate per day by approximately 74-88% after 12 weeks of treatment
90%
Urge Incontinence: (Involuntary urine leakage) Up to 90% of patients reported improvements with many eliminating episodes of incontinence. The number of episodes per day was reduced by approximately 83% after 12 weeks of treatment
21-35%
Nocturia (frequent nighttime urination): After 12 weeks of therapy, nighttime urination in patients decreased by approximately 21-35%
Research
Prospective, Randomized, Multicenter Trial of Peroneal Electrical Transcutaneous Neuromodulation vs Solifenacin in
Treatment-naıve Patients With Overactive Bladder
Conclusions: Peroneal electrical transcutaneous neuromodulation is a safe and effective method for overactive bladder treatment associated with a significantly
lower incidence of treatment-related adverse events compared to solifenacin and a considerably better benefit-risk profile.
Differences between brain responses to peroneal electrical transcutaneous neuromodulation and transcutaneous tibial nerve stimulation, two treatments for overactive bladder
Conclusions: Peroneal eTNM®, but not TTNS, induces the activation of brain structures that were previously implicated in neural control of the of bladder filling and play an important role in the ability to cope with urgency. The therapeutic effect of peroneal eTNM® could be exerted, at least in part, at the
supraspinal level of neural control.
Brain Response Induced by Peroneal Electrical
Transcutaneous Neuromodulation Invented for
Overactive Bladder Treatment, as Detected by
Functional Magnetic Resonance Imaging
Conclusions: Our study provides evidence that peroneal electrical Transcutaneous Neuromodulation elicits activation of brain structures that have been previously implicated in the perception of bladder fullness and that play a role in the ability to cope with urinary urgency. Our data suggest that neuromodulation at the level of supraspinal control of the lower urinary tract may contribute to the treatment effect of peroneal electrical Transcutaneous Neuromodulation in patients with OAB.
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